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Sunday, November 3, 2013

George Mason Tops Bowie State Lady Bulldogs 98-60 in Basketball Exhibition

FAIRFAX, Va. - The Bowie State University women's basketball team fell short of victory in a 98-60 exhibition loss to Division I George Mason University on Sunday afternoon at the Patriot Center. Juniors Ashley Castle (Brooklyn, N.Y.) and Denver Clyde (Glen Burnie, Md.) led the Bulldogs with 14 and 12 points respectively.

The Lady Bulldogs kept the game close in the first 10 minutes of action, leading by three twice at 19-16 and 21-18 on back-to-back layups by graduate student Uchechi Ahaiwe (Riverdale, Md.). However, the Colonials went on a 14-0 run and never were threatened after that.

The first half featured four ties and nine lead changes before George Mason settled down and pulled away.

Bowie State trailed 45-27 at the break. The Lady Bulldogs shot 28 percent (9-32) from the field in the first half, compared to 47 percent (14-30) for George Mason. Castle led BSU in scoring for the first half with eight points while Clyde had six points and seven boards at intermission.

George Mason stretched out their lead in the second half, outscoring Bowie State 53-33. The Patriots finished the contest shooting 50 percent (28-56) from the floor and held a 48 to 37 rebounding advantage.

All 13 Bowie State players saw action and scored in the game. Uchechi scored eight points and grabbed five rebounds in just 10 minutes. Senior Alessandra Flores Conway (Hagerstown, Md.) chipped in seven points, sophomore Alauna Jackson (Ellicott City, Md.) scored four and junior Ashley Davis (Odenton, Md.) contributed three points. Six other Lady Bulldog players added two points each.

Clyde and senior Moriah Goodman led Bowie State on the glass with seven rebounds each.

Four of five George Mason starters scored in double figures with Cierra Strickland (Forestville, Md.) leading the Colonials with 21 points. Taylor Brown (Bowie, Md.) and Janaa Pickard (Philadelphia, Pa.) recorded 19 and 16 points respectively and Talisha Watts (Lynchburg, Va.) added a double-double of 11 points and 11 rebounds.

Bowie State begins the regular season on Friday (November 8th) hosting Nyanck (N.Y.) College at 6 pm in the A.C. Jordan Arena.

Bowie State vs George Mason (11/3/13 at Patriot Center)

* * * C O R R E C T E D     S T A T S * * *


Official Basketball Box Score



Official Basketball Box Score Bowie State vs George Mason 11/3/13 2:00 pm at Patriot Center -------------------------------------------------------------------------------- VISITORS: Bowie State 0-0 TOT-FG 3-PT REBOUNDS ## Player Name FG-FGA FG-FGA FT-FTA OF DE TOT PF TP A TO BLK S MIN 1 PHIPPS,Kiera........ * 0-1 0-1 2-2 1 1 2 3 2 1 3 0 0 17 2 SMITH,ReVen......... 1-5 0-0 0-0 0 0 0 2 2 0 1 0 0 5 3 CASTLE,Ashley....... * 5-11 2-5 2-2 0 2 2 3 14 2 7 0 1 26 5 BURLEY,Alisha....... 1-2 0-1 0-1 0 3 3 5 2 1 4 1 1 11 10 FLORES,Alessandra... 1-5 1-2 4-4 1 1 2 4 7 0 3 0 0 17 11 HEARD,Robin......... 1-3 0-0 0-3 0 1 1 3 2 0 0 0 0 13 14 DAVIS,Ashley........ * 1-4 1-2 0-0 0 0 0 1 3 0 0 0 0 20 23 McINTOSH,Jasmine.... 1-4 0-1 0-0 0 0 0 4 2 1 1 0 0 17 24 CLYDE,Denver........ * 4-16 0-4 4-5 4 3 7 1 12 1 2 0 1 25 32 JACKSON,Alauna...... 2-2 0-0 0-2 0 0 0 1 4 0 1 0 0 11 33 GOODMAN,Moriah...... * 0-2 0-0 2-2 3 4 7 3 2 0 1 0 0 21 34 BONAPARTE, Briana... 0-2 0-0 0-3 0 2 2 1 0 0 0 0 0 7 55 AHAIWE,Uchechi...... 4-4 0-0 0-0 2 3 5 5 8 0 0 1 0 10 TEAM................ 3 3 6 Totals.............. 21-61 4-16 14-24 14 23 37 36 60 6 23 2 3 200 TOTAL FG% 1st Half: 9-32 28.1% 2nd Half: 12-29 41.4% Game: 34.4% DEADB 3-Pt. FG% 1st Half: 3-9 33.3% 2nd Half: 1-7 14.3% Game: 25.0% REBS F Throw % 1st Half: 6-11 54.5% 2nd Half: 8-13 61.5% Game: 58.3% 3 -------------------------------------------------------------------------------- HOME TEAM: George Mason 0-0 TOT-FG 3-PT REBOUNDS ## Player Name FG-FGA FG-FGA FT-FTA OF DE TOT PF TP A TO BLK S MIN 5 MOHAMED, Reana...... 4-5 1-2 4-4 1 2 3 0 13 0 1 0 0 22 11 PICKARD, Janaa...... * 3-9 1-2 9-12 1 6 7 4 16 1 0 5 0 24 12 PETTY-EVANS, Denisha 1-4 1-3 3-6 0 4 4 4 6 1 2 0 4 19 13 DUNNINGAM, Char-Dell 0-2 0-0 2-5 1 2 3 2 2 1 1 0 2 17 22 JACOBS, Kyana....... * 3-5 1-2 2-4 0 2 2 3 9 2 4 0 1 25 23 STRICKLAND, Cierra.. * 7-13 0-3 7-8 2 3 5 1 21 1 1 1 2 27 31 BROWN, Taylor....... * 6-12 2-5 5-7 0 1 1 3 19 4 1 0 2 31 32 JACKSON, Brittany... 0-0 0-0 0-0 1 0 1 0 0 0 0 0 1 0 40 WATTS, Talisha...... * 4-5 0-0 3-6 4 7 11 3 11 0 1 0 2 28 44 DAWSON,Dominique.... 0-1 0-0 1-4 1 2 3 2 1 0 1 0 0 7 TEAM................ 4 4 8 Totals.............. 28-56 6-17 36-56 15 33 48 22 98 10 12 6 14 200 TOTAL FG% 1st Half: 14-30 46.7% 2nd Half: 14-26 53.8% Game: 50.0% DEADB 3-Pt. FG% 1st Half: 2-9 22.2% 2nd Half: 4-8 50.0% Game: 35.3% REBS F Throw % 1st Half: 15-22 68.2% 2nd Half: 21-34 61.8% Game: 64.3% 10 -------------------------------------------------------------------------------- Officials: Technical fouls: Bowie State-None. George Mason-None. Attendance: 325 Score by Periods 1st 2nd Total Bowie State................... 27 33 - 60 George Mason.................. 45 53 - 98 Exhibition Points in the paint-BOWIE 24,MASON 32. Points off turnovers-BOWIE 8,MASON 28. 2nd chance points-BOWIE 11,MASON 10. Fast break points-BOWIE 0,MASON 4. Bench points-BOWIE 27,MASON 22. Score tied-4 times. Lead changed-9 times. Last FG-BOWIE 2nd-03:23, MASON 2nd-00:25. Largest lead-BOWIE by 3 1st-11:49, MASON by 38 2nd-00:25.

The Hidden Cause of Cancer Most People Ignore

Cancer Defeated Publications

The Hidden Cause of Cancer
Most People Ignore

Today I’m going to talk about two diseases that may seem to be a world apart. Yet numerous studies suggest the two are often linked. It’s not completely clear why, but people with a common, preventable health condition are FAR more likely to be diagnosed with cancer. 
And the risk is most threatening of all with one of the most dreaded types of cancer - pancreatic cancer. Although it extends to many kinds of cancer. 
Read on to find out more…


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The evidence is now more compelling than ever that diabetes and cancer are closely related… much like two troublemaking siblings with no parents around to keep an eye on them.
This means that a great deal of cancer is preventable. It doesn’t just happen by chance. It doesn’t drop from a clear blue sky. You can prevent diabetes (and reverse it, if you already have it).

    We’ve known for a long time that diabetes is linked to vascular (i.e. circulatory) complications. Think heart attack, stroke, blindness, gangrene and limb loss, kidney disease, and sexual dysfunctioni.

    Probably this list won’t surprise you — given how many people have diabetes these days.

       But now there’s an established linked between diabetes and non-vascular complications, like cancer, which don’t have much to do with your blood vessels. If you have diabetes, you’re not only more likely to get cancer… you’re also more likely to die from cancer.
According to Pankaj Shah, M.D., at the Mayo Clinic, "Evidence suggests that these 2 common conditions coexist more often than would be expected to occur by chance."
That’s an understatement…
400% more pancreatic cancer,
300% more blood cancer…
The U.S. Centers for Disease Control and Prevention (CDC) found that 16 percent of diabetic men and 17 percent of diabetic women get cancer, versus just 7 and 10 percent respectively, in the overall population. That means for men, diabetes is associated with more than double the risk of cancer. For women, the cancer risk increase is about 70 percent.

    Dr. Chaoyang Li from the CDC said that even after accounting for external factors like age, race, and smoking and drinking habits, diabetics are far more likely to get colon, pancreatic, rectum, urinary bladder, kidney, breast and prostate cancers than their non-diabetic counterparts.

    The strength of the cancer-diabetes link depends on the type of cancer. The most dramatic increased risk is to pancreatic cancer…with diabetic men apparently 400 percent more likely to get pancreatic cancer than non-diabetics. In plain English, diabetes makes you five times as likely to be diagnosed with pancreatic cancer.

    And diabetic women are 300 percent more likely to develop blood cancer than non-diabetic women.
More likely to get cancer…
And far less likely to survive it…
A 2008 study by diabetes expert Dr. Fred Brancati of Johns Hopkins showed that the death rate from cancer is about 40 percent higher in diabetics than in the general population.
The one exception to this general rule is prostate cancer. The data suggest that diabetes may actually be protective against prostate cancer — which seems like a mystery.
Personally, I’d opt to skip diabetes and take my chances with prostate cancer versus say, pancreatic… as prostate is a far less aggressive form of cancer.
The 3 primary "suspects" in
the cancer-diabetes connection
Once you realize there’s a connection between diabetes and cancer, the next logical question is, "What is the mechanism?"

    Researchers cite three suspects:
  • Insulin. Many researchers think high insulin is the primary culprit. Type-2 diabetics are insulin resistant. When you have diabetes, your body drives up its insulin production to compensate, often over a period of years. High insulin is associated with higher cancer risk. And in animals, high insulin is a growth factor for tumors.

    Your pancreas makes insulin, which then goes straight to your liver… a key factor why these two organs have such high insulin levels. Some experts think that’s what makes these two organs so vulnerable to cancer.

    High insulin also boosts sex hormone production by the ovaries, which may be the hidden link to ovarian, uterine, and breast cancers. A 2008 study suggests that people with higher than normal insulin receptors are at higher risk of cancer.

    Harvard professor Edward Giovannucci, M.D. calls it a double whammy… Insulin encourages cell growth, discourages cell death, and boosts proliferation of cancer cells. At the same time, insulin also makes cancer cells more invasive and likely to spread.
  • Blood glucose.  Though insulin is the primary suspect, high blood glucose may play a role too. It’s a well-known fact that cancer cells are adept at slurping up glucose from your bloodstream, no insulin required. Since glucose (sugar) fuels cancer, high blood sugar levels may feed cancer cell growth.
  • Inflammation. Diabetics and those who are obese usually have signs of chronic inflammation, based on C-reactive protein and other inflammatory markers in their blood.
But there may be a couple of other culprits too. And some are related to these three "suspects".
How Well Do You Control These Secondary Factors?
There’s also the possibility of shared risk factors, that is, the same things may cause both cancer and diabetes. And it’s another "chicken or the egg factor"… No one knows for sure which comes first — the cancer or the diabetes.

    Many people never even suspect they have diabetes until they’re screened for it after a cancer diagnosis. Sometimes sudden onset of diabetes occurs at the same time a person is diagnosed with cancer.

    Which of the following shared risk factors do you have? While two of these are beyond your control, the other three are within your control. 
  • Age. The older you are, the more at risk you are for both cancer and diabetes.
  • Gender. Men get more cancer overall, and have a slightly higher diabetes risk.
  • Weight. Can increase your risk for both conditions.
  • Activity. Sedentary lifestyles can boost your risks of both.
  • Smoking. It’s linked to several kinds of cancer, as well as type-2 diabetes.
Stubborn weight gain is one of your most obvious early hints of faulty insulin signaling and high blood sugar levels. Pay attention to this "advanced warning" now, and you may be able to avoid a world of regret later.
The hidden factor you probably won’t
hear about from your doctor
In March 2013 the U.S. FDA announced it was investigating a potential link between a popular class of diabetes drugs called DPP-4 inhibitors and pancreatitis (inflammation of the pancreas) and pre-cancerous cellular changes to the pancreasii. Previous studies also show these drugs are linked to thyroid, colon, melanoma, and prostate cancer.
These drugs, also known as incretin mimetics, work by mimicking incretin hormones. They inhibit the enzyme DPP-4, a natural tumor suppressor. As your blood sugar rises, these drugs prompt your pancreas to release insulin.
Here’s how they may cause cancer:
  • DPP-4 is a natural tumor suppressor
  • These drugs shut it down, so by taking them you continuously inhibit one of your body’s natural cancer suppressors.
  • The drug information for Januvia, one of the drugs in this class, says it inhibits the DPP-4 enzyme for 24 hours. Patients are expected to take it daily, meaning the tumor suppressor is constantly shut down.
Therefore, you’ll want to ask yourself…
Do you need these drugs in the first place?
Today there’s overwhelming evidence that you own the ability to prevent and control diabetes without the use of any drugs in the first place. Entire books have been written about it.

    In fact, simple lifestyle remedies exist for many health problems… while poorly tested drugs can cause disastrous results — like cancer — for millions.
 Here are some lifestyle changes you can make to reverse your diabetes — and potentially save yourself from a cancer diagnosis as well.
  1. Slash carbohydrates from your diet (breads, cereals, pasta, rice…). You can eat almost unlimited portions of most vegetables without gaining weight, with the exception of higher-carb vegetables such as carrots, potatoes, and beets, which you may want to limit. Limit portion sizes of other foods. This is also true for nearly every beverage besides water — soda, juices, alcoholic drinks, etc. Stay far away.
  2. Get at least 2 1/2 hours of moderately brisk exercise per week. It’s one of the best ways to reduce your insulin regulating problems. Why not start with a 30-minute walk after work every day? Besides being better insulin control, it’ll help you de-stress from your day.
  3. Get 6 to 8 hours of refreshing sleep every night. Sleep deprivation is strongly linked to both diabetes and cancer.
  4. Make sure your vitamin D levels are 50 to 70 ng/ml based on the 25(OH)D test. This range has been identified as best for optimal healthiii. Lower levels are associated with both cancer and diabetes.
  5. Make every effort to lose some weight and keep it off. Even a mere five or ten pounds can make a big difference. Obviously more is better, especially if you’re substantially above your ideal weight.  Rejoice in small improvements, and don’t let jokes or criticism from other people bother you.
  6. Quit smoking if you’re a smoker. It is strongly linked to both diseases.
  7. Stick with your plan for 3 months. Expect incremental changes while your body adjusts to better insulin and blood sugar controls. This is a marathon to better health, not a sprint.
So here’s the bottom line:
Avoid diabetes, and your chances for sidestepping cancer dramatically improve.
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footnotes:








Health Disclaimer: The information provided above is not intended as personal medical advice or instructions. You should not take any action affecting your health without consulting a qualified health professional. The authors and publishers of the information above are not doctors or health-caregivers. The authors and publishers believe the information to be accurate but its accuracy cannot be guaranteed. There is some risk associated with ANY cancer treatment, and the reader should not act on the information above unless he or she is willing to assume the full risk.

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Bowie State Trounces Lincoln 76-19 in Home Football Finale

BOWIE, Md. – Bowie State held Lincoln to 267 total yards in a 76-19 home finale thumping at Bulldogs Stadium on Saturday afternoon. The 76 points is the second highest (83 vs. Fairleigh Dickinson – 1975) in Bowie State history. The Bulldogs won their second straight game to improve to 4-5 overall and 2-4 in the CIAA. The Lions dropped their seventh straight to fall to 1-8 and 0-6.

Bulldogs senior Jared Johnston led the assault completing 13-of-23 passes for 226 yards, setting a new BSU season passing yards record. The prior record (1,538) was held by former Bulldog Clifton “Dominique” Budd in 2010.

In terms of team superlatives, the Bulldogs set a new single game record for first downs with 27, surpassing the old mark of 25 set back in 1982 versus St. Paul’s College. BSU fell just shy of setting a record in offensive yards, rolling up 557.

The Bulldogs defense limited the Lincoln Lions to 30 yards rushing and 237 yards through the air. Lincoln was 8-for-18 on third down conversions in the contest.

Bowie State opened the scoring on a blocked Lincoln field goal attempt by sophomore Curtis Pumphrey (Laurel, Md.). Pumphrey returned it 70 yards for a defensive touchdown and the extra point by junior Mario Diaz-Aviles (Washington, D.C.) gave the Bulldogs the early 7-0 lead. 
  
Lincoln responded with a five-play, 82 yard drive that resulted in a Lions touchdown. The big play during the drive was 74 yard pass and catch by Doug Cook (Miami, Fla.) to Akeem Jordan (Washington, D.C.). After two incomplete passes, Cook connected with Jordan for a 13-yard score.

A Diaz-Aviles 25-yard field goal at the 6:43 mark of the first quarter moved the Bulldogs lead to 10-6. The BSU defense forced a Lincoln three and out setting up the Bulldogs next score.

Bowie State redshirt sophomore Kendall Jefferson (Temple Hills, Md.) scored the first of his two touchdowns on the afternoon, scampering in from 14 yards out to put the score at 17-6.

Cook’s second and final TD pass came with 1:45 left in the opening quarter when he flipped a high end zone corner pass to Anthony Green (Chester, Pa.) for an eight yard score. Kyle Jaske (Escondido, Calif.) added the extra point to trim the Bulldogs lead to 17-13.

The Bulldogs exploded for 35 second quarter points and strolled into halftime with a cushy 52-13 stronghold. Bowie State scored on all five of their second quarter possessions.

Bowie State put together a nine-play, 78 yard drive to begin the third quarter, capped off by Jefferson six-yard touchdown run to extend the Bulldogs lead to 59-13.

The Bulldogs defense held Lincoln again on their next drive and Jefferson returned a Jaski punt 53 yards for another BSU score and a 66-13 advantage heading into the final quarter.

Bowie State’s reserves saw plenty of action in the fourth quarter. Of the 18 Bulldog plays run over the final 15 minutes, 17 were runs. Freshman Stephen Willis toted the ball nine times for 68 yards, second best for the game.

Senior Keith Brown scored his second touchdown (12th of the season) from one-yard out on BSU’s first possession of the fourth quarter, padding the Bulldogs lead at 73-13.

Bowie State’s final points on Senior Day came via a 39 yard field goal by Diaz-Aviles with 4:45 remaining in the game.

Lincoln had two more possessions over in the final minutes of the game and managed to score with three seconds left on the clock. With 2:22 remaining, Cook continued to air it out with nine straight passes. The biggest play during the Lions final drive was a 23 yard reception by Jordan down to the BSU five yard line. Three plays later, Steve Gilliam (Bowie, Md.) rushed around the right end for a four-yard TD run and final 76-19 score.   

Cook completed 20-of 41 passes for a game-high 232 yards and two scores, but he was sacked six times. Jordan recorded game-highs of nine receptions and 153 yards to lead the Lions receivers.

Tyahir Mitchell (Wilmington, Del.) and Gavin Lampkin (Baltimore, Md.) paced the Lincoln defense with 10 tackles apiece.
      
Redshirt freshman Kevaugn Townsend (Ft. Washington, Md.) led the Bowie State defense with seven tackles, including one behind the line-of-scrimmage and a forced fumble. Redshirt sophomore Denzel Prince (Temple Hills, Md.) had five tackles, four solo; while senior Delante White (Temple Hills, Md.) and sophomore Ronald Baines (Clementon, N.J.) had four tackles each.

Sophomore Garry Cropper (Odenton, Md.) had a team-high five catches for 66 yards and one score to lead the BSU receivers. Brown led the Bulldogs with 28 rushes for 143 yards, his fourth game over 100 yards and is currently 106 yards shy of 1,000 for the season.

The Bulldogs close out the 2013 season next Saturday (November 9th) at Elizabeth City State University. Game time is 1:00 pm in ECSU’s Roebuck Stadium.

George Washington Beats Bowie State 85-68 in Bulldogs' Final Exhibition

WASHINGTON, D.C. – Bowie State University seniors Carlos Smith (Baltimore, Md.) and Ray Gatling (Oxon Hill, Md.) led the Bulldogs with 15 and 13 points respectively, but George Washington University tasted victory with an 85-68 exhibition victory at the Charles E. Smith Center on Saturday afternoon.

Nemanja Mikic, Maurice Creek and Isaiah Armwood combined for 42 points to lead a balanced offense. Mikic led all players with 19 points and five 3-pointers, while Creek and Armwood both posted double-doubles. Creek finished with 17 points, 11 rebounds and three steals, and Armwood stuffed the stat sheet with 16 points, 16 rebounds and seven blocks.

George Washington trailed by four early against a Bowie State team that is picked to win the CIAA Northern Division and visited Duke for an exhibition last week, but quickly took the lead for good with back-to-back threes from Mikic and Armwood during a 10-0 run for a 13-7 advantage 3:38 into the contest.

The Colonials' first-half lead peaked at 13 twice - first at 43-40 on Creek's 15-foot bank shot, then at 49-36 on a Cartagena jumper - before settling at 12 points, 53-41, at intermission. GW shot 50 percent (17-34) and had six players score at least eight points by the break, led by nine from Mikic and Savage, as well as eight points and nine boards by Armwood and eight points and eight rebounds by Creek.

Bowie State shot 36 percent from the floor in the first half (13-36) with Gatling scoring 10 points in the first 20 minutes while senior Julian Williams (Washington, D.C.) added nine first half points.

GW opened the second half with an 8-2 run capped by a pair of Creek free throws for its largest advantage of the game at 61-43 with 17:19 left.

Bowie State utilized relentless pressure - scoring 25 points off 30 George Washington turnovers in the game - and an up-tempo offense to stay within striking distance throughout the second stanza, climbing to within single digits at 66-57 with just over 11 minutes to play.

However, the Colonials allowed just 11 points over the final 11 minutes, while Cartagena and Mikic both hit key triples, and Creek and Armwood each broke loose for fast-break dunks to clinch the 17-point victory.

George Washington dominated the glass with a 54-34 rebounding advantage, and finished 46 percent (27-59) from the field, including 8-of-21 from deep, and 74 percent at the foul line (23-31), while holding BSU to 34 percent shooting (24-70) and 5-of-18 behind the arc (0-7 in the second half).

The Bulldogs begin the regular season on Friday, November 8th against host Fairmont (W.Va.) State in the opening round of the Fighting Falcons Classic. Game time is 3 p.m.

Looking for ways to make chemotherapy safer

Gold Nanoparticles May Hold Key
To Safer Forms of Chemotherapy

Most folks know that chemotherapy drugs kill cancer cells AND healthy cells.
Because these drugs don't discriminate, cancer patients frequently experience hair loss... foggy thinking... nausea and vomiting... and other problems caused when chemo drugs zap healthy cells.
Now, new research may point to the precious metal GOLD as an effective way to scrub cancer cells from your body! It all involves continued research and improvements to treatments known as metallodrugs. Let me explain…
Continued below…


Why Most Health Foods are a Waste of Money
By Lee Euler
    You can take vitamins, minerals, and antioxidants by the handful and stillsuffer poor health. Now we know why. Our diets lack a vital food -- a type of nutrient that even alternative doctors don’t know about. Thanks to this supplement, a mother’s lifelong migraines disappeared, and a man with "terminal" kidney cancer was alive 15 years later. He’s just one of thousands of cancer patients who have taken this supplement and seen remarkable results.

    There’s more: It’s one of the most popular pain relievers in Germany, used by that country’s Olympic team to help athletes get rid of pain and accelerate healing from sports injuries. It outperforms prescription blood clot drugs—in my opinion, patients should take this supplement instead of blood-thinning drugs like warfarin. And it even helps 9 out of 10 autistic children. The mother of a 7-year-old autistic child starting giving him this supplement after reading my Special Report The Missing Ingredient—and he started speaking after having been nonverbal his whole life!

    How can ONE supplement possibly do all this? Just ask yourself: What if you were getting NO vitamins in your diet? You’d be very sick. This nutrient is just as important and you’re getting almost none. Read more here about The Missing Ingredient, and consider trying it yourself.

Missing Ingredient

Drugs that contain metals have been used since the 1970s to treat some types of cancer. Most commonly this involves platinum compounds such as cisplatin and its derivatives.
According to the National Institutes of Health (NIH), cisplatin (brand name Platinol®) is appropriate to treat various cancers including:
  • Bladder
  • Brain
  • Head and neck
  • Lung
  • Ovaries
  • Testicles
Cisplatin binds to DNA and interferes with the cell division process. The damaged DNA signals DNA repair mechanisms to swing into action, which in turn activate apoptosis—the process that causes cancer cells to self-destruct.
But because it’s not very selective, cisplatin can also stunt the growth of normal body cells too.
This causes many of the same side effects seen with other chemotherapy drugs, and in some cases can lead to kidney problems and hearing loss.
Now there’s a chance that new research has uncovered a more effective method for using metals to clobber cancer.  According to a Brooklyn College statement, Dr. Maria Contél, associate professor of chemistry, recently received a $1.4 million NIH grant to continue researching a gold-titanium combination that could be used to fight renal and prostate cancer.
The researchers previously received a $467,860 three-year grant from NIH to create an alternative cancer therapy that is less toxic than platinum-based compounds.
“It means the NIH appreciated our productivity under the first grant and warmed up to the idea of studying organometallic compounds as potential chemotherapeutics. It is perhaps changing minds at the NIH,” Dr. Contel said.
So how would the new combo
metal treatment work?
Combination therapeutics includes administering two or more drugs in order to reach different targets.
Doctors could inject a medication consisting of one metal to target cell nuclei and another to damage the cell powerhouse, the mitochondria.  The aim would be to damage cancer cell DNA and thereby activate the cell’s self-repair process, which actually results in apoptosis or “cell suicide” instead.
Dr. Contel said that for the new grant, her team produced “preliminary results on a gold/titanium treatment that inhibited certain mechanisms of prostate and kidney cancer in a way different to cisplatin while killing the cancer cells.”
In essence, the gold-titanium combination would be used to target and destroy different parts of cancer cells while leaving other cells unharmed.
But Contel warns that it’s no small feat to go from researching this type of treatment to developing a successful commercial drug.
"If you’re amazingly lucky, you may see one of your findings enter the market. Only 5 of 5,000 compounds evaluated in preclinical studies will get the approval of the FDA. The whole process to develop a new drug takes an average of 10 to 15 years," Contel said.
Other groups join the ‘gold rush’
for cancer cures!
In addition to Dr. Contel’s research into combining metal therapies, other groups are researching the use of gold nanoparticles as a promising cancer treatment.
Cytimmune Sciences of Rockville, MD recently published preliminary results of a phase 1 clinical trial of a targeted chemotherapy treatment called Aurimuneis.
Their treatment attaches a molecule of the tumor-killing agent called tumor necrosis factor alpha (TNF) to gold nanoparticles.
The researchers also bind a molecule of Thiol-derivatized polyethylene glycol (PEG-THIOL) to hide the TNF nanoparticle from the immune system. The gold nanoparticles are able to travel through the patient’s  bloodstream without the gatekeepers of the immune system kicking them out. This ensures that the tumor-killing substance will be delivered to the disease site.
A Cytimmune statement said the Phase 1 clinical trial data indicate that Aurimuneis “preferentially delivered to the site of disease with minimal accumulation in healthy tissue.”
A team of University of Arizona researchers has developed another targeted therapy for delivering cancer drugs inside gold-coated liposomes.
The invention was spearheaded by Dr Marek Romanowski, an associate professor of biomedical engineering in the University of Arizona (UA) College of Engineering in Tucson.
Dr. Romanowski worked with graduate students Xenia Kachur and Sarah Leung to develop a method for gold-coated liposomes to deliver cancer drugs in controlled doses without harming healthy body cells.
Liposomes are tiny capsules used to transport materials inside cells. In chemotherapy treatment, they enclose the cancer drug in a skin made of fats already present in human cells.
This covering prevents the patient’s immune system from launching an attack before the chemo drugs are delivered to the cancer site.
Only after the liposomes enter openings in the cancer tumors do they break down, releasing the drug that kills the cancer cells.  The researchers experimented with using infrared light to control the amount of drugs that are released at one time.
All of these efforts are designed to improve cancer drug delivery and lessen the harmful effects of chemotherapy on healthy tissue.
Of course, you might want to consider alternative cancer treatments that don’t subject any part of your body to harsh synthetic drugs. But it is good to know that scientists continue their quest for less invasive and abrasive treatment regiments!

Saturday, November 2, 2013

Bowie State 76 - Lincoln 19 (FOOTBALL FINAL)

 

Scoring Summary

 
Scoring Summary (Final)
BOWIE STATE UNIVERSITY BULLDOGS 2013
Lincoln vs Bowie State (Nov 2, 2013 at Bowie, MD)

Lincoln (1-8,0-6) vs. Bowie State (4-5,2-4)
Date: Nov 2, 2013  • Site: Bowie, MD  • Stadium: Bulldogs  •  Attendance: 1085
Score by Quarters Score 
Lincoln  13 0 0 6 19 
Bowie State  17 35 14 10 76 
SCORING SUMMARY  LUPA -BSU  
1st 13:12 BSU  PUMPHREY,Curtis 70 yd blocked FG return (DIAZ-AVILES,Mario kick) 
       0 - 7 
 11:42 LUPA  JORDAN,Akeem 13 yd pass from COOK,Doug (JORDAN,Akeem rush failed) 
      5 plays, 82 yards, TOP 1:21 6 - 7 
 06:43 BSU  DIAZ-AVILES,Mario 25 yd field goal 
      11 plays, 61 yards, TOP 4:51 6 - 10 
 04:21 BSU  JEFFERSON,Kendall 14 yd run (DIAZ-AVILES,Mario kick) 
      4 plays, 32 yards, TOP 1:17 6 - 17 
 01:45 LUPA  GREEN,Anthony 8 yd pass from COOK,Doug (JASKI,Kyle kick) 
      6 plays, 65 yards, TOP 2:30 13 - 17 
2nd 13:20 BSU  CROPPER,Garry 24 yd pass from JOHNSTON,Jared (DIAZ-AVILES,Mario kick) 
      3 plays, 34 yards, TOP 0:59 13 - 24 
 12:03 BSU  BROWN,Keith 18 yd pass from JOHNSTON,Jared (DIAZ-AVILES,Mario kick) 
      3 plays, 34 yards, TOP 1:03 13 - 31 
 09:08 BSU  BROWN,Keith 1 yd run (DIAZ-AVILES,Mario kick) 
      5 plays, 26 yards, TOP 1:21 13 - 38 
 04:41 BSU  QUARRIE,Phillip 10 yd run (DIAZ-AVILES,Mario kick) 
      6 plays, 38 yards, TOP 2:19 13 - 45 
 00:29 BSU  JOHNSTON,Jared 16 yd run (DIAZ-AVILES,Mario kick) 
      8 plays, 91 yards, TOP 2:28 13 - 52 
3rd 11:10 BSU  JEFFERSON,Kendall 6 yd run (DIAZ-AVILES,Mario kick) 
      9 plays, 78 yards, TOP 3:43 13 - 59 
 09:50 BSU  JEFFERSON,Kendall 53 yd punt return (DIAZ-AVILES,Mario kick) 
       13 - 66 
4th 13:08 BSU  BROWN,Keith 1 yd run (DIAZ-AVILES,Mario kick) 
      7 plays, 35 yards, TOP 2:37 13 - 73 
 04:45 BSU  DIAZ-AVILES,Mario 39 yd field goal 
      12 plays, 65 yards, TOP 6:11 13 - 76 
 00:03 LUPA  GILLIAM,Steve 4 yd run (JASKI,Kyle kick failed) 
      10 plays, 59 yards, TOP 2:19 19 - 76 
Kickoff time: 1:00 pm  • End of Game: 4:01  • Total elapsed time: 3:01
Referee: R. Straughter  •  Umpire: Derek Hatten  •  Linesman: A. Randolph  •  Line judge: Sean Cherry  •  Back judge: Lawrence Hill  •  Field judge: John Holmes  •  Side judge: Chris Wulff  •
Temperature: 66  • Wind: W @6 mph • Weather: Partly Cloudy
Next Lincoln Game: Saturday (11/9) vs. Chowan - 1:00 pm
Next Bowie State Game: Saturday (11/9)
at Elizabeth City State - 1:00 pm